Should i skip my weekly rapamycin the week before or after a flu shot?
A number of studies have found that rapamycin improves the effectiveness of flu vaccines. Not an expert, and I think flu vaccines change so its unlikely there was a study for this years vaccine. Joan Mannick has some youtube discussions about this effect.
In a human study measuring rapamycin effects on boosting vaccine response, I think they stopped the rapa at least 2 weeks before the vaccination. Of course they never started back up again after vaccination. So I would stop it at least 2 weeks prior and two weeks after to get a good antibody response. It takes couple of weeks for antibody response to occur.