When it comes to drug interactions, there is only a limited amount of drugs to watch out for. These include cyclosporine, grapefruit juice, and inducers and inhibitors of CYP3A4 and P-glycoprotein (P-gp). CYP3A4 is a key enzyme which metabolizes most drugs; P-gp is a transporter which significantly influences distribution and bioavailability of many drugs.
Statins that do not use the CYP3A4 isoenzyme metabolic pathway are referred to as statin non-3A4 substrates (pravastatin, fluvastatin, and rosuvastatin)….I take it from this information that some statins are an issue with Rapa? I use Rosuvastatin so I am good here, I guess.