# Auto-immune effects? **URL:** \ **Category:** Rapamycin\ **Created:** [October 13, 2024, 12:29am UTC](https://community.gethealthspan.com/t/auto-immune-effects/1694 "2024-10-13T00:29:31Z")\ **Posts on this page:** 4\ **Page:** 1
**Author:** ![dblotii444](https://avatars.discourse-cdn.com/v4/letter/d/b38774/32.png) [@dblotii444](https://community.gethealthspan.com/u/dblotii444)\ **Post date:** [October 13, 2024, 12:29am UTC](https://community.gethealthspan.com/t/auto-immune-effects/1694/1 "2024-10-13T00:29:31Z")
Should Rapamycin protocol for Senescence have any effect on auto immune disorders like colitis, Crohns, rheumatoid arthritus, eczema, etc? ---
**Author:** ![dblotii444](https://avatars.discourse-cdn.com/v4/letter/d/b38774/32.png) [@dblotii444](https://community.gethealthspan.com/u/dblotii444)\ **Post date:** [December 22, 2024, 2:11pm UTC](https://community.gethealthspan.com/t/auto-immune-effects/1694/2 "2024-12-22T14:11:42Z")
I am surprised that there is no information about this. ---
**Author:** ![Npeelma1](https://avatars.discourse-cdn.com/v4/letter/n/b487fb/32.png) [@Npeelma1](https://community.gethealthspan.com/u/Npeelma1)\ **Post date:** [January 10, 2025, 2:59pm UTC](https://community.gethealthspan.com/t/auto-immune-effects/1694/3 "2025-01-10T14:59:11Z")
There is info on this. Google mTOR pathway in autoimmune disorders. You’ll get a lot of research/scholarly articles but the mTOR pathway is involved with proliferation, inflammation, etc. It’s activated in the synovial fluid in RA patients contributing to the cause of joint destruction. ---
**Author:** ![dblotii444](https://avatars.discourse-cdn.com/v4/letter/d/b38774/32.png) [@dblotii444](https://community.gethealthspan.com/u/dblotii444)\ **Post date:** [January 10, 2025, 3:54pm UTC](https://community.gethealthspan.com/t/auto-immune-effects/1694/4 "2025-01-10T15:54:08Z")
> [@Npeelma1](#): > > mTOR pathway in autoimmune disorders What should be expected, overall, for the effect on Rapamycin on auto-immune disorders