# Applying rapamycin cream only to certain areas of face **URL:** \ **Category:** General\ **Created:** [August 23, 2023, 6:53pm UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541 "2023-08-23T18:53:14Z")\ **Posts on this page:** 4\ **Page:** 1
**Author:** ![Alex](https://avatars.discourse-cdn.com/v4/letter/a/db5fbb/32.png) [@Alex](https://community.gethealthspan.com/u/Alex)\ **Post date:** [August 23, 2023, 6:53pm UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541/1 "2023-08-23T18:53:14Z")
If you apply rapamycin to a small area of the face eg half a cheek - will that patch only respond to the rapamycin? Or would the rapamycin absorb into the skin and affect the whole face? Thanks ---
**Author:** ![Dr.Bart](https://yyz2.discourse-cdn.com/flex036/user_avatar/community.gethealthspan.com/dr.bart/32/131_2.png) [@Dr.Bart](https://community.gethealthspan.com/u/Dr.Bart)\ **Post date:** [September 10, 2023, 5:45pm UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541/2 "2023-09-10T17:45:34Z")
Topical agents typically do not traverse across the skin that I know of unlike infections. We use topical agents like steroids, anti-fungal, etc. and it’s always has been localized to the application area. ---
**Author:** ![shriyabakhshi](https://yyz2.discourse-cdn.com/flex036/user_avatar/community.gethealthspan.com/shriyabakhshi/32/141_2.png) [@shriyabakhshi](https://community.gethealthspan.com/u/shriyabakhshi)\ **Post date:** [September 19, 2023, 8:00pm UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541/3 "2023-09-19T20:00:00Z")
Hi Alex! This is Shriya from the Healthspan Clinical Team. As a topical agent, our rapamycin cream is not absorbed into the bloodstream in a discernible way based on testing rapamycin concentration levels. Therefore topical rapamycin has a more localized effect. To see the full effects of topical 0.2% rapamycin we recommend using enough cream to cover the entire face/neck, or other areas that have been subjected to sun damage. If you are looking to get a broader effect of rapamycin, I recommend looking into our oral rapamycin protocols. Please reach out to our healthcare team if you have any additional questions! ---
**Author:** ![Alex](https://avatars.discourse-cdn.com/v4/letter/a/db5fbb/32.png) [@Alex](https://community.gethealthspan.com/u/Alex)\ **Post date:** [September 20, 2023, 4:47am UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541/4 "2023-09-20T04:47:28Z")
That’s very useful - thank you!