# Latest **URL:** https://community.gethealthspan.com/latest.md?page=3 [Latest](https://community.gethealthspan.com/latest.md) · [Categories](https://community.gethealthspan.com/categories.md) · [Tags](https://community.gethealthspan.com/tags.md) **Page:** 4 --- ## [Rapamycin and Fisetin](https://community.gethealthspan.com/t/rapamycin-and-fisetin/378)
**Author:** [@Boulderjoe](https://community.gethealthspan.com/u/Boulderjoe)\ **Replies:** 5\ **Last updated:** [January 23, 2024, 6:44pm UTC](https://community.gethealthspan.com/t/rapamycin-and-fisetin/378 "2024-01-23T18:44:25Z")
Rapamycin and Fisetin treatment at the same time? Fisetin treatment is only 2 days every 30. Does anyone take both in the same week? --- ## [Combining Rapamycin/Metformin with Forskolin and Sodium Butyrate to induce somatic cells to pluripotency](https://community.gethealthspan.com/t/combining-rapamycin-metformin-with-forskolin-and-sodium-butyrate-to-induce-somatic-cells-to-pluripotency/708)
**Author:** [@Mekongcola](https://community.gethealthspan.com/u/Mekongcola)\ **Replies:** 2\ **Last updated:** [December 2, 2023, 8:14pm UTC](https://community.gethealthspan.com/t/combining-rapamycin-metformin-with-forskolin-and-sodium-butyrate-to-induce-somatic-cells-to-pluripotency/708 "2023-12-02T20:14:33Z")
Any thoughts on whether the use of small molecule reprogramming in conjunction with a Rapamycin and/or Metformin regimen produces partial iPSC? --- ## [The Longevity Benefits of Acarbose and Rapamycin—New Findings from the NIA ITP](https://community.gethealthspan.com/t/the-longevity-benefits-of-acarbose-and-rapamycin-new-findings-from-the-nia-itp/172)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 5\ **Last updated:** [December 1, 2023, 2:13pm UTC](https://community.gethealthspan.com/t/the-longevity-benefits-of-acarbose-and-rapamycin-new-findings-from-the-nia-itp/172 "2023-12-01T14:13:41Z")
The National Institute on Aging Interventions Testing Program (ITP) was designed to be the most exhaustive testing framework and system to evaluate whether longevity molecules extend longevity in mice and understand the … --- ## [Rapamycin compounded? Enteric coated?](https://community.gethealthspan.com/t/rapamycin-compounded-enteric-coated/607)
**Author:** [@Jpchurch34](https://community.gethealthspan.com/u/Jpchurch34)\ **Replies:** 8\ **Last updated:** [December 1, 2023, 1:01am UTC](https://community.gethealthspan.com/t/rapamycin-compounded-enteric-coated/607 "2023-12-01T01:01:58Z")
Dr. Peter Attia podcast The Drive episode 272. #272 ‒ Rapamycin: potential longevity benefits, surge in popularity, unanswered questions, and more | David Sabatini, M.D., Ph.D. and Matt Kaeberlein, Ph.D. - Peter Attia N… --- ## [Periodic Testing](https://community.gethealthspan.com/t/periodic-testing/25)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 1\ **Last updated:** [November 4, 2023, 7:44pm UTC](https://community.gethealthspan.com/t/periodic-testing/25 "2023-11-04T19:44:31Z")
When it comes to periodic blood testing we recommend a blood test every 6 weeks if possible. We recommend this because it allows us to catch any abnormalities before they worsen. Additionally, please send your results to… --- ## [Positive benefits of rapamycin treatment](https://community.gethealthspan.com/t/positive-benefits-of-rapamycin-treatment/47)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 3\ **Last updated:** [October 24, 2023, 2:37am UTC](https://community.gethealthspan.com/t/positive-benefits-of-rapamycin-treatment/47 "2023-10-24T02:37:05Z")
In terms of the positive benefits that our patients regularly tell us about, joint inflammation is the number one thing patients notice. The other benefit is autoimmune issues like psoriasis clearing up. Rapamycin is an … --- ## [Topical Rapamycin concentration](https://community.gethealthspan.com/t/topical-rapamycin-concentration/653)
**Author:** [@Luis123](https://community.gethealthspan.com/u/Luis123)\ **Replies:** 1\ **Last updated:** [October 20, 2023, 6:27pm UTC](https://community.gethealthspan.com/t/topical-rapamycin-concentration/653 "2023-10-20T18:27:38Z")
Is it possible to request a higher concentration? I have asked without a response? If anyone can answer would be well appreciated. --- ## [Flu shot? Rapamycin](https://community.gethealthspan.com/t/flu-shot-rapamycin/647)
**Author:** [@Jpchurch34](https://community.gethealthspan.com/u/Jpchurch34)\ **Replies:** 2\ **Last updated:** [October 20, 2023, 3:30pm UTC](https://community.gethealthspan.com/t/flu-shot-rapamycin/647 "2023-10-20T15:30:47Z")
Should i skip my weekly rapamycin the week before or after a flu shot? --- ## [Rapamycin effects effects on hair?](https://community.gethealthspan.com/t/rapamycin-effects-effects-on-hair/272)
**Author:** [@Ginger](https://community.gethealthspan.com/u/Ginger)\ **Replies:** 3\ **Last updated:** [October 11, 2023, 12:37am UTC](https://community.gethealthspan.com/t/rapamycin-effects-effects-on-hair/272 "2023-10-11T00:37:02Z")
I was wondering if rapamycin causes hair loss or slow hair growth. --- ## [Rapamycin: longevity benefits, surge in popularity, unanswered questions, and more](https://community.gethealthspan.com/t/rapamycin-longevity-benefits-surge-in-popularity-unanswered-questions-and-more/629)
**Author:** [@jeff](https://community.gethealthspan.com/u/jeff)\ **Replies:** 1\ **Last updated:** [October 9, 2023, 4:38pm UTC](https://community.gethealthspan.com/t/rapamycin-longevity-benefits-surge-in-popularity-unanswered-questions-and-more/629 "2023-10-09T16:38:31Z")
--- ## [Rapamycin in the news](https://community.gethealthspan.com/t/rapamycin-in-the-news/54)
**Author:** [@jeff](https://community.gethealthspan.com/u/jeff)\ **Replies:** 5\ **Last updated:** [October 5, 2023, 2:27am UTC](https://community.gethealthspan.com/t/rapamycin-in-the-news/54 "2023-10-05T02:27:31Z")
Use this topic to post links to articles and studies on rapamycin. --- ## [Applying rapamycin cream only to certain areas of face](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541)
**Author:** [@Alex](https://community.gethealthspan.com/u/Alex)\ **Replies:** 3\ **Last updated:** [September 20, 2023, 4:47am UTC](https://community.gethealthspan.com/t/applying-rapamycin-cream-only-to-certain-areas-of-face/541 "2023-09-20T04:47:28Z")
If you apply rapamycin to a small area of the face eg half a cheek - will that patch only respond to the rapamycin? Or would the rapamycin absorb into the skin and affect the whole face? Thanks --- ## [In case of infection or surgery](https://community.gethealthspan.com/t/in-case-of-infection-or-surgery/45)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 2\ **Last updated:** [September 19, 2023, 8:01pm UTC](https://community.gethealthspan.com/t/in-case-of-infection-or-surgery/45 "2023-09-19T20:01:21Z")
We recommend pausing for the duration of an infection and wait at least a week until you feel 100%. Once this period has concluded you’re good to resume taking your medications. --- ## [Does MTor inhibit male fertility? What would be the recommended does](https://community.gethealthspan.com/t/does-mtor-inhibit-male-fertility-what-would-be-the-recommended-does/471)
**Author:** [@zyonix](https://community.gethealthspan.com/u/zyonix)\ **Replies:** 1\ **Last updated:** [September 19, 2023, 8:00pm UTC](https://community.gethealthspan.com/t/does-mtor-inhibit-male-fertility-what-would-be-the-recommended-does/471 "2023-09-19T20:00:58Z")
One of the concerns I have is that mTor is a central regulator of spermatogenesis. Emerging Role for Mammalian Target of Rapamycin in Male Fertility - PMC mTOR plays an important role in male fertility by integrating an… --- ## [Therapeutic phlebotomy for longevity](https://community.gethealthspan.com/t/therapeutic-phlebotomy-for-longevity/283)
**Author:** [@svprice](https://community.gethealthspan.com/u/svprice)\ **Replies:** 2\ **Last updated:** [September 19, 2023, 7:58pm UTC](https://community.gethealthspan.com/t/therapeutic-phlebotomy-for-longevity/283 "2023-09-19T19:58:22Z")
Hi all, There’s increasing evidence that donating/giving blood is beneficial for longevity: Each additional blood donation is associated with a 7.5% reduction in mortality risk Iron cannot naturally be removed from th… --- ## [Rapamycin cream and surgery scars](https://community.gethealthspan.com/t/rapamycin-cream-and-surgery-scars/539)
**Author:** [@kytexas](https://community.gethealthspan.com/u/kytexas)\ **Replies:** 1\ **Last updated:** [September 19, 2023, 7:55pm UTC](https://community.gethealthspan.com/t/rapamycin-cream-and-surgery-scars/539 "2023-09-19T19:55:54Z")
Would it be advisable to apply topical rapamycin to scars after surgery? I would of course wait till the incision healed but has there been any research on the use of the cream and healing scars. I am having reconstruct… --- ## [Hypermobile joints and Rapamycin](https://community.gethealthspan.com/t/hypermobile-joints-and-rapamycin/521)
**Author:** [@CynicallyRealistic](https://community.gethealthspan.com/u/CynicallyRealistic)\ **Replies:** 1\ **Last updated:** [September 19, 2023, 7:54pm UTC](https://community.gethealthspan.com/t/hypermobile-joints-and-rapamycin/521 "2023-09-19T19:54:31Z")
I’ve had hypermobile joints my whole life, it was a bit of a party trick as a teenager! But my dad also has hypermobile joints and has had to have replacement knees and shoulders as he aged. Basically the collagen the we… --- ## [Rapamycin Dosing Regime](https://community.gethealthspan.com/t/rapamycin-dosing-regime/44)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 4\ **Last updated:** [August 2, 2023, 7:02pm UTC](https://community.gethealthspan.com/t/rapamycin-dosing-regime/44 "2023-08-02T19:02:05Z")
There is no data that dictates whether or not rapamycin should be taken at the same time of day. Additionally, rapamycin can be taken with or without food, so either work. Our dosing protocol is to be taken 1x a week (e… --- ## [Healthspan Founder on the Wise Athletes Podcast Discussing Rapamycin for Longevity](https://community.gethealthspan.com/t/healthspan-founder-on-the-wise-athletes-podcast-discussing-rapamycin-for-longevity/448)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 0\ **Last updated:** [June 28, 2023, 10:01pm UTC](https://community.gethealthspan.com/t/healthspan-founder-on-the-wise-athletes-podcast-discussing-rapamycin-for-longevity/448 "2023-06-28T22:01:14Z")
We had a great discussion with Joe Lavelle from the Wise Athletes podcast. We covered a lot, and hopefully was informative for folks looking to understand the mechanisms of rapamycin and understanding how we can manipula… --- ## [Acarbose and stomach discomfort](https://community.gethealthspan.com/t/acarbose-and-stomach-discomfort/41)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 12\ **Last updated:** [June 7, 2023, 2:49am UTC](https://community.gethealthspan.com/t/acarbose-and-stomach-discomfort/41 "2023-06-07T02:49:25Z")
Yes, a lot of people have these GI issues in response to acarbose, unfortunately. Take 1 time a day with food. To avoid GI issues when starting, avoid excessive carbohydrates during your first week. --- ## [How do you supplement your rapamycin treatment?](https://community.gethealthspan.com/t/how-do-you-supplement-your-rapamycin-treatment/24)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 2\ **Last updated:** [May 31, 2023, 9:32pm UTC](https://community.gethealthspan.com/t/how-do-you-supplement-your-rapamycin-treatment/24 "2023-05-31T21:32:23Z")
How to you build on and take advantage of your rapamycin treatment? Do you supplement it with a particular workout regimen or perhaps with other vitamins and supplements? --- ## [Six minutes of high-intensity exercise could delay the onset of Alzheimer's disease](https://community.gethealthspan.com/t/six-minutes-of-high-intensity-exercise-could-delay-the-onset-of-alzheimers-disease/199)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 3\ **Last updated:** [May 30, 2023, 10:20pm UTC](https://community.gethealthspan.com/t/six-minutes-of-high-intensity-exercise-could-delay-the-onset-of-alzheimers-disease/199 "2023-05-30T22:20:06Z")
Six minutes of high-intensity exercise substantially increases BDNF - a neurotrophic factor that helps keep the brain young. Six 40-second intervals at 100% of VO2 max increased BDNF 4- to 5-fold more than light exerci… --- ## [Everything about canker sores](https://community.gethealthspan.com/t/everything-about-canker-sores/48)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 7\ **Last updated:** [May 26, 2023, 11:26pm UTC](https://community.gethealthspan.com/t/everything-about-canker-sores/48 "2023-05-26T23:26:01Z")
In terms of negative side effects, a small percentage of patients have canker sores inside of their mouths. These seem to be temporary in the small percentage of patients who get them. For the patients that do get canke… --- ## [Rapamycin and Fasting](https://community.gethealthspan.com/t/rapamycin-and-fasting/42)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 2\ **Last updated:** [May 26, 2023, 12:55am UTC](https://community.gethealthspan.com/t/rapamycin-and-fasting/42 "2023-05-26T00:55:23Z")
Hey, there’s been no extensive studies on this. As such I would recommend doing the fast and treating it as a dose of rapamycin. Then a week from your last fasting day, take your first dose of rapamycin. The fast and the… --- ## [Fasting and rapamycin](https://community.gethealthspan.com/t/fasting-and-rapamycin/387)
**Author:** [@Boulderjoe](https://community.gethealthspan.com/u/Boulderjoe)\ **Replies:** 2\ **Last updated:** [May 24, 2023, 5:06pm UTC](https://community.gethealthspan.com/t/fasting-and-rapamycin/387 "2023-05-24T17:06:38Z")
Does anyone here use fasting along with rapamycin? I do a 24 hour fast (breakfast to breakfast) on day 2 of my 7 day cycle with rapamycin. --- ## [The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine](https://community.gethealthspan.com/t/the-adverse-metabolic-effects-of-branched-chain-amino-acids-are-mediated-by-isoleucine-and-valine/372)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 1\ **Last updated:** [May 19, 2023, 10:45pm UTC](https://community.gethealthspan.com/t/the-adverse-metabolic-effects-of-branched-chain-amino-acids-are-mediated-by-isoleucine-and-valine/372 "2023-05-19T22:45:23Z")
https://www.cell.com/cell-metabolism/fulltext/S1550-4131(21)00166-2?\_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413121001662%3Fshowall%3Dtrue Low-protein diets promote metabolic health in ro… --- ## [Does rapamycin have full government FDA approval for use as intended as longevity treatment?](https://community.gethealthspan.com/t/does-rapamycin-have-full-government-fda-approval-for-use-as-intended-as-longevity-treatment/37)
**Author:** [@Jake](https://community.gethealthspan.com/u/Jake)\ **Replies:** 5\ **Last updated:** [May 19, 2023, 8:19pm UTC](https://community.gethealthspan.com/t/does-rapamycin-have-full-government-fda-approval-for-use-as-intended-as-longevity-treatment/37 "2023-05-19T20:19:57Z")
In terms of the FDA approval for longevity, rapamycin is an off-label use. The FDA approves drugs for an indicated use to either cure or prevent a particular illness or condition. Because extending lifespan is not a co… --- ## [Rapamycin and Muscle Growth: Glass Lab Review of Anabolic Resistance](https://community.gethealthspan.com/t/rapamycin-and-muscle-growth-glass-lab-review-of-anabolic-resistance/385)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 0\ **Last updated:** [May 17, 2023, 12:07am UTC](https://community.gethealthspan.com/t/rapamycin-and-muscle-growth-glass-lab-review-of-anabolic-resistance/385 "2023-05-17T00:07:23Z")
In the intricate tapestry of aging, one phenomenon stands out prominently: anabolic resistance. As we journey through the years, our bodies exhibit a reduced capacity to construct new muscle protein, even in the presen… --- ## [Exploring the Impact of High-Protein Diets on Longevity and Metabolic Function](https://community.gethealthspan.com/t/exploring-the-impact-of-high-protein-diets-on-longevity-and-metabolic-function/373)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 0\ **Last updated:** [May 7, 2023, 7:37pm UTC](https://community.gethealthspan.com/t/exploring-the-impact-of-high-protein-diets-on-longevity-and-metabolic-function/373 "2023-05-07T19:37:30Z")
https://gethealthspan.com/blog/articles/effects-of-high-protein-diets-on-longevity/7r4te9qpag4yimrppmyhvw/ Overview A common belief is that a high-protein diet will facilitate an increase in muscle mass, strength, and f… --- ## [Small dose of whey protein with meal improves postprandial glucose levels and suppresses appetite (in type 2 diabetics))](https://community.gethealthspan.com/t/small-dose-of-whey-protein-with-meal-improves-postprandial-glucose-levels-and-suppresses-appetite-in-type-2-diabetics/371)
**Author:** [@daniel\_tawfik](https://community.gethealthspan.com/u/daniel_tawfik)\ **Replies:** 2\ **Last updated:** [May 7, 2023, 1:51am UTC](https://community.gethealthspan.com/t/small-dose-of-whey-protein-with-meal-improves-postprandial-glucose-levels-and-suppresses-appetite-in-type-2-diabetics/371 "2023-05-07T01:51:12Z")
This study aimed to investigate the effects of small doses of intact and hydrolyzed whey protein co-ingested with mixed-nutrient breakfast and lunch meals on postprandial glycemic and appetite responses in men with typ… [Previous page](https://community.gethealthspan.com/latest.md?page=2) [Next page](https://community.gethealthspan.com/latest.md?page=4)